merkelgama

The expression of the special AT-rich sequence-binding protein SATB2 was analyzed in MCC n 20 together with other forms of skin cancer. Approximately 25 Danish patients are diagnosed each year. Merkel Cell Carcinoma A Review And Update On Current Concepts Diagnostic Histopathology Merkel cell carcinoma MCC is a rare aggressive skin cancer with neuroendocrine differentiation. Merkel cell carcinoma immunohistochemistry . Although rare compared with other skin cancers the incidence of Merkel cell carcinoma in the USA tripled between 1986. Immunohistochemical and ultrastructural analyses are usually helpful in differentiating these neoplasms. Distinction between primary cutaneous Merkel cell carcinoma and metastatic neuroendocrine carcinoma in the skin is based on the immunohistochemical profile of the tumor and clinical pathologic correlation ie. Merkel cell tumors stain positively for NSE as would any APUD cell. Risk factors include long-term ultraviolet UV exposure Merkel c...